Coffee restores memory loss in mice with Alzheimer’s symptoms

Who likes coffee has one more reason for the next cup: researchers at the University of South Florida (USF) in the United States, we analyzed mice with symptoms similar to Alzheimer’s disease who ingested amounts of caffeine equivalent to five cups of coffee per day had a reversal in the frame memory loss and decreased production of amyloid beta-protein linked to the disease. Gary Arendash, a neuroscientist at the University, said the results show a new aid for the disease: “The discovery shows that caffeine could be a ‘treatment’ feasible for Alzheimer’s disease, and not just a prevention strategy.

” “That’s important because caffeine is a safe drug for most people, easily enters the brain, and appears to directly affect the disease process,” adds Arendash. The study was conducted with 55 mice genetically engineered to develop memory problems similar to those reported by patients with Alzheimer’s disease. When the mice began to exhibit memory problems at 18 or 19 months – equivalent to 70 years of humans – the researchers started to take caffeine in the water half the rats. After two months, the mice that received caffeine had better results on tests of memory and motor skills, while mice that received normal drinking water continued to go badly in the tests.

“These are the most promising experiments done with rats on Alzheimer’s disease, and show that caffeine rapidly reduces beta-amyloid protein in the blood,” says Huntington Potter, Center for Alzheimer’s Research and USF. The research showed that the protein was reduced by almost 50% in the caffeine-treated mice. Researchers do not yet know if a smaller amount than 500 milligrams daily would be enough, but Arendash says that for most people, this moderate consumption does not bring adverse effects to the health of most people. A previous study showed that caffeine reduces the levels of a protein involved in the development of Alzheimer’s disease in the brain and in the blood of rats who had symptoms of the disease. Both surveys add up to a first survey, which showed that the substance ingested in early adulthood prevented the formation of memory problems.


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